| Citation: | Shaher Momani, Rabha W. Ibrahim. A $ (Q,\tau)$-FRACTIONAL AGING MODEL WITH MEMORY EFFECTS AND ADAPTIVE HEALING DYNAMICS[J]. Journal of Applied Analysis & Computation, 2026, 16(3): 1621-1642. doi: 10.11948/20250185 |
We propose a novel $(q, \tau)$-fractional aging model that incorporates memory-dependent physiological decay and healing dynamics through a deformable time structure. The model generalizes classical aging laws by introducing a tunable fractional order $ \alpha $ and deformation parameters $ q $ and $ \tau $, which control the depth and scale of biological memory. External interventions, modeled as healing inputs, are integrated via generalized Mittag-Leffler kernels to capture both cumulative and periodic therapeutic effects. Simulation results demonstrate that composite healing strategies significantly delay decline and improve physiological resilience. Parameter sensitivity analysis reveals that the model flexibly adapts to different aging profiles by adjusting memory and deformation parameters. Using synthetic data, we validate the model's fitting accuracy through numerical optimization, achieving high fidelity with low residual error. The key advantage of the $(q, \tau)$-fractional approach lies in its ability to encode long-term memory effects and nonuniform biological time flow, enabling realistic modeling of aging phenomena beyond exponential decay. The framework is robust under noisy conditions and extensible to data-driven calibration, making it a powerful tool for biomedical aging analysis, intervention design, and longitudinal health forecasting.
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Comparison of exponential decay (
Plot of the
Decay of physiological state
Comparison of aging trajectories with and without external healing term
Comparison of
Simulated trajectories of physiological state
Time evolution of physiological state
Comparison of observed (blue dots), true (dashed), and fitted (solid) physiological state
Residuals of the fitted
Simulation of recovery dynamics under different memory parameters
Recovery dynamics under the